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Search / Trial NCT02939586

The Effect of Haemodialysis in Sleep Apnoea

Launched by JOHN HUNTER HOSPITAL · Oct 18, 2016

Trial Information

Current as of July 21, 2025

Completed

Keywords

Sleep, Sleep Apnoea, Haemodialysis, Haemodiafiltration, End Stage Kidney Disease

ClinConnect Summary

Sleep Problem in Dialysis Patients Sleep apnoea is a significant issue in patients with end stage kidney disease. Evidence suggests that up to 80% of dialysis patients have sleep apnoea \[1\], yet the standard haemodialysis treatment does not improve the symptoms of sleep disturbance in most patients \[2\].

Sleep disturbance is specifically associated with poor quality of life (QoL) \[4\]; decreased mental and physical function, and adversely impact survival \[5-7\]. Recent data also suggest that the low oxygen state resulting from sleep apnoea can exaggerate the deterioration of kidney fu...

Gender

ALL

Eligibility criteria

  • Inclusion criteria
  • Individuals receiving maintenance haemodialysis under the care of Nephrology Department, John Hunter Hospital \& Manning Base Hospital
  • Have received dialysis for more than 3 months.
  • Greater than 18 years of age
  • Able to provide informed consent
  • Satisfactory written and spoken English language skills
  • AHI score between 15-29 or above 30 if the participant a. declines sleep apnoea treatment after discussing with their physician, b. would like to be involved in the trial whilst awaiting an appointment in the sleep clinic.
  • Exclusion criteria
  • Acute dialysis or acutely unwell patients
  • Home dialysis patients
  • Unable to participate in the study in the opinion of the participant's primary Nephrologist or due to language barrier or cognitive impairment.
  • Already on treatment for sleep-disordered breathing
  • Woman who are pregnant

About John Hunter Hospital

John Hunter Hospital, a leading tertiary healthcare facility located in New South Wales, Australia, is dedicated to advancing medical research and enhancing patient care through innovative clinical trials. With a strong focus on collaboration and patient-centered approaches, the hospital engages in a wide range of studies across various medical disciplines, aiming to translate research findings into effective treatments and improved health outcomes. Committed to ethical standards and rigorous scientific methodology, John Hunter Hospital plays a pivotal role in contributing to the body of medical knowledge while ensuring the highest level of safety and care for trial participants.

Locations

Newcastle, New South Wales, Australia

Patients applied

0 patients applied

Trial Officials

Vanessa McDonald, PhD

Principal Investigator

Academic Clinician/University of Newcastle

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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