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Search / Trial NCT02952443

Exercise Intervention to Reverse Frailty

Launched by UNIVERSITY OF BRITISH COLUMBIA · Nov 1, 2016

Trial Information

Current as of May 04, 2025

Unknown status

Keywords

ClinConnect Summary

Frailty is term widely used to denote a multidimensional syndrome associated with the loss of physical and cognitive reserve capacity that makes an individual vulnerable to cumulative clinical health conditions. The level of frailty can be classified as one of three phenotypes (non-frail; pre-frail, frail) using the Cardiac Health Study frailty index (CHS). The CHS assesses the number of physical deficits expressed by an individual. These deficits include (unexplained weight loss, poor grip strength, feelings of exhaustion, slowed gait, and low levels of physical activity). An individual wh...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Female
  • 65-95 years of age
  • Free of any serious injury in the last 6 months
  • Deemed to express the pre-frailty phenotype, meaning they are classified as: Pre-frail according to the CHS and "Vulnerable" and/or "Mildly Frail" according to the CFS
  • Confirmation of pre-frailty based-upon walking speed of 1.0-1.5 meters/second
  • Assessed as healthy for exercise according to responses from the PAR-Q+
  • Are consider safe for exercise based on the evaluation by a Certified Exercise Physiologist (CEP).
  • Do not have any cognitive impairment, a score of ≥26 (total possible score 30) indicates normal cognitive function as measured by MoCA tool
  • Participants must be able to speak and read English fluently
  • Exclusion Criteria:
  • Male
  • Below 65 years of age or above 95
  • Have suffered a serious injury in the last 6 months
  • Not deemed pre-frail based on scores from the CHS and CFS
  • Walking speed slower or faster than 1.0-1.5 m/s
  • Assessed as unhealthy for exercise according to responses from the PAR-Q+
  • Are consider unsafe for exercise based on the evaluation of the CSEP-CEP
  • Have possible cognitive impairment as measured by the MoCA tool (score \<26)

About University Of British Columbia

The University of British Columbia (UBC) is a leading research institution located in Vancouver, Canada, renowned for its commitment to advancing health sciences through innovative research and education. As a prominent clinical trial sponsor, UBC leverages its interdisciplinary expertise and state-of-the-art facilities to conduct rigorous clinical studies aimed at improving patient outcomes across various medical fields. The university fosters collaborations with healthcare professionals, industry partners, and community stakeholders to translate research findings into practical applications, thereby contributing to the global advancement of medicine and public health.

Locations

Kelwona, British Columbia, Canada

Patients applied

0 patients applied

Trial Officials

Gareth R Jones, PhD

Principal Investigator

UBC Okanagan

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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