Chronic Periodontitis and Polycystic Ovary Syndrome
Launched by BEZMIALEM VAKIF UNIVERSITY · Nov 1, 2016
Trial Information
Current as of September 24, 2025
Completed
Keywords
ClinConnect Summary
RESULTS:
Salivary 8-OHdG levels in the PCOSCP and CP groups were statistically higher than those in both the PCOSPH and the PH groups (P \< 0.05). There was no statistical difference between the PCOSCP, CP, and PCOSPH groups with regard to salivary MDA and TAS levels (P \> 0.05). Highest serum 8-OHdG and MDA levels and lowest serum TAS levels were seen in the PCOSCP group (P \< 0.05). Serum 8-OHdG and MDA levels in the PCOSPH group were higher than those in both systemically healthy groups (PH and CP) (P \< 0.05). Salivary TAS levels were highest (P \< 0.05) in the PH group. There was no s...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Newly diagnosed non-obese PCOS patients
- • Never smokers
- • Had no history of systemic disease
- • BMI\<25 kg/m2
- • Participants had ≥20 teeth present.
- Exclusion Criteria:
- • Pregnancy
- • Lactation
- • Hemoglobin A1c (HbA1c) ≥ 6.5%
- • 2-h oral glucose tolerance test (OGTT-2h) ≥200
- • Cushing syndrome, non-classic congenital adrenal hyperplasia, hyperprolactinemia, thyroid dysfunction, and androgen-secreting tumors
- • Any drug use within the past 6 months
- • Periodontal treatment within the past 6 months
About Bezmialem Vakif University
Bezmialem Vakif University is a prominent academic institution based in Istanbul, Turkey, dedicated to advancing medical research and education. As a clinical trial sponsor, the university leverages its state-of-the-art facilities and a multidisciplinary team of experts to conduct innovative research that aims to improve patient outcomes and enhance therapeutic strategies. Bezmialem Vakif University is committed to adhering to rigorous ethical standards and regulatory guidelines, ensuring the integrity and reliability of its clinical trials while fostering collaboration with global research communities. Through its initiatives, the university seeks to contribute significantly to the field of medicine and public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
İstanbul, Fatih, Turkey
Patients applied
Trial Officials
Nesrin Saruhan, PhD
Principal Investigator
Eskisehir Osmangazi Üniversitesi
Cenk Fatih Çanakcı, Prof
Study Director
Ataturk University
Saime Ozbek Sebin, Dr
Principal Investigator
Ataturk University
Humeyra Canakcı, Dr
Principal Investigator
Buhara Hastanesi
Metin İngeç, Prof
Principal Investigator
Ataturk University
Ufuk Sezer, Phd
Principal Investigator
Özel Klinik
Ebru Saglam, PhD
Principal Investigator
Saglik Bilimleri Universitesi
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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