Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty
Launched by KAT GENERAL HOSPITAL · Nov 14, 2016
Trial Information
Current as of July 21, 2025
Unknown status
Keywords
ClinConnect Summary
Introduction
Various adjuvants like morphine, fentanyl, clonidine, ketamine are being used since long for improvement of intraoperative anaesthesia and postoperative analgesia following spinal anaesthesia. On the other hand, such adjuvants have their associated adverse effects. As a result, search for an effective adjuvant is still going on. Dexmedetomidine (DEX), a selective α2-adrenoceptor agonist, has analgesic and sedative effects and nowadays, is being studied for its adjuvant action in subarachnoid anaesthesia.
As far as DEX is concerned, it has been reported that it can be administ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients selected for total knee arthroplasty of approximately one and half hour (90 min) duration under spinal anaesthesia.
- • Patients who belong to American Society of Anaesthesiologists (ASA) physical status grade I and II
- • Exclusion Criteria:• Patients with coagulation and neurological disorders
- • Patients allergic to DEX
- • Patients showing unwillingness for spinal anaesthesia
About Kat General Hospital
Kat General Hospital is a leading healthcare institution dedicated to advancing medical research and enhancing patient care through innovative clinical trials. With a commitment to excellence, the hospital collaborates with multidisciplinary teams of experienced healthcare professionals to conduct rigorous studies across various therapeutic areas. Kat General Hospital prioritizes patient safety and ethical standards, ensuring that all clinical trials are conducted in compliance with regulatory requirements. By fostering a culture of collaboration and transparency, the hospital aims to contribute to the development of new treatments and therapies that improve health outcomes for diverse patient populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kifissia, , Greece
Patients applied
Trial Officials
Efi Stavropoulou
Study Chair
KAT GENERAL HOSPITAL OF ATTICA
Cathrin Chazapis
Study Chair
KAT General Hospital of Athens
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials