ClinConnect ClinConnect Logo
Search / Trial NCT02982876

Airway Stents for Excessive Dynamic Airway Collapse

Launched by BETH ISRAEL DEACONESS MEDICAL CENTER · Dec 2, 2016

Trial Information

Current as of July 09, 2025

Enrolling by invitation

Keywords

Silicone Airway Stent Metallic Airway Stent

ClinConnect Summary

Study Design

This randomized controlled trial will be conducted at Beth Israel Deaconess Medical Center (BIDMC) in accordance with Good Clinical Practice Standards and under IRB supervision. We plan to enroll total of 48 patients with EDAC randomized by a computer generated system to either intervention group (airway stent) or medical management group.

Description of the study

Previous to appointment all patients will have Airway CT scan, 6 minute walk test and pulmonary function test as per protocol and standard of care.

Enrollment

Patients with severe EDAC who remain symptomatic desp...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patient with sever symptomatic EDAC (collapse \>90% of the airway during exhalation at dynamic CT scan)
  • Age \> 18 years
  • Exclusion Criteria:
  • Patients who have not been well managed from their respiratory comorbidities (asthma, COPD, obstructed sleep apnea, GERD, relapsing polychondritis)
  • Current respiratory infection
  • Resting bradycardia (\<50 beats/min), frequent multifocal PVCs, complex ventricular arrhythmia, sustained SVT
  • Dysrhythmia that might pose a risk during exercise or training
  • Any disease or condition that interferes with completion of initial or follow-up assessments

About Beth Israel Deaconess Medical Center

Beth Israel Deaconess Medical Center (BIDMC) is a leading academic medical center located in Boston, Massachusetts, affiliated with Harvard Medical School. Renowned for its commitment to cutting-edge research and innovation in healthcare, BIDMC fosters a collaborative environment that integrates patient care, education, and scientific investigation. The center actively sponsors clinical trials across a variety of disciplines, aiming to advance medical knowledge and improve patient outcomes. With a focus on translational medicine, BIDMC's research initiatives engage multidisciplinary teams to address complex health challenges and translate findings into effective therapeutic strategies.

Locations

Patients applied

0 patients applied

Trial Officials

Adnan Majid, MD

Principal Investigator

Beth Israel Deaconess Medical Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials