99Tc-MDP Treatment for Knee Osteoarthritis

Launched by XINHUA HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE · Dec 12, 2016

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called 99Tc-MDP for people with knee osteoarthritis, a common type of arthritis that causes pain and stiffness in the knee. The researchers want to see how effective this treatment is compared to a well-known medication called celecoxib. Osteoarthritis can become more serious as people age, and effective treatments are important for improving quality of life.

To participate in this trial, you need to have painful osteoarthritis and meet certain health criteria, including having a specific level of bone activity in the knee. The study is open to adults of all ages, but individuals with knee joint replacements, certain types of joint infections, or other specific joint issues are not eligible. If you join the study, you will receive one of the treatments being tested and will be closely monitored to see how well it works for your knee pain. This trial is currently recruiting participants, so if you or someone you know is interested, it could be a way to contribute to finding new treatment options for knee osteoarthritis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Participants with painful osteoarthritis;
• • 2. The standard uptake value (SUV) of OA related knee greater than 10 on 18F- sodium fluoride bone scan;
• • 3. Participants voluntarily participate in the trial, and signed the informed consent.
• Exclusion Criteria:
• • 1. Knee joint replacement;
• • 2. Inflammatory arthritis or joint infection of knee;
• • 3. Nervous joint disease;
• • 4. Fracture of joint;
• • 5. Gout arthritis of the knee;
• • 6. Traumatic arthritis.