Implications of Circadian Variation of Human Endocannabinoid Levels on Obesity Risk

Launched by UNIVERSITY OF CHICAGO · Dec 19, 2016

Keywords

ClinConnect Summary

This clinical trial is studying how the timing of when we eat affects our body's natural rhythms and how we process energy, which may play a role in obesity. Researchers want to understand if eating at different times of the day influences levels of certain fats in our bodies, which are linked to enjoying food and maintaining a healthy metabolism.

To join this study, participants need to be between 18 and 62 years old, sleep 7 to 9 hours each night, and not have any sleep disorders or conditions like diabetes. They also should not take any medications, have a history of certain health issues, or have dietary restrictions. The trial is not yet recruiting participants, but if you qualify and choose to participate, you can expect to be involved in research that could help us learn more about how our eating habits relate to weight and health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • self-report sleeping between 7-hrs/night and 9-hrs/night, between 22:00 and 08:00
• • no previously diagnosed sleep disorders (including obstructive sleep apnea (OSA))
• • no existing diagnosis of prediabetes or diabetes
• • no history of endocrine dysfunction
• • no history of psychiatric, cardiovascular, or eating disorders
• • must not have a gastro-intestinal disease that requires dietary adjustment
• • currently taking no medications (including birth control)
• Exclusion Criteria:
• • drug and nicotine use, habitual alcohol use of more than 2 drinks per day, and caffeine intake of more than 300 mg per day
• • anyone who has participated in medically managed weight loss program within the past year
• • anyone who has undergone bariatric surgery
• • must not have dietary restrictions
• • must not work night shifts or crossed any time zones in the month prior to the study.