Valvular Heart Disease Registry Study in Second Affiliated Hospital of ZheJiang University

Launched by SECOND AFFILIATED HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY · Jan 4, 2017

Keywords

ClinConnect Summary

The Valvular Heart Disease Registry Study at the Second Affiliated Hospital of Zhejiang University is looking into how common valvular heart disease is among hospitalized adults in China, as well as its characteristics, risk factors, treatment options, and outcomes. This study aims to gather important information that can help doctors better understand and treat patients with conditions like aortic stenosis, mitral regurgitation, and more.

To participate in this study, you must be at least 18 years old and currently hospitalized with moderate or severe valvular heart disease, or have had heart valve surgery or a diagnosis of endocarditis, which is an infection of the heart lining. If you join, you’ll be part of a group that will be monitored to see how your condition progresses and how effective different treatments are. It's important to know that some patients who are critically ill or unable to follow up will not be eligible to participate. This research will help improve care for future patients with heart valve issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Hospitalized patients over 18 years old meet one of the following conditions.
• • 1. moderate or above valvular heart disease as defined by echocardiography: 1.1 Aortic stenosis, moderate or above, or valve area ≤1.5cm2, or maximal jet velocity ≥3.0m/sec, or mean pressure gradient ≥20mmHg, 1.2 Aortic regurgitation, moderate or above, or jet width ≥25% of left ventricular outflow tract, or regurgitant volume ≥30ml/beat, or regurgitant fraction ≥30%, 1.3 Mitral stenosis, moderate or above, or valve area ≤2.0cm2, 1.4 Mitral regurgitation, moderate or above, or effective regurgitant orifice ≥0.2cm2, or regurgitant volume ≥30ml/beat, or regurgitant fraction ≥30%, 1.5 Tricuspid stenosis, moderate or above, or valve area ≤1.0cm2, 1.6 Tricuspid regurgitation, moderate or above, or central jet area ≥5.0cm2, 1.7 Pulmonic stenosis, moderate or above, or maximal jet velocity \>4m/sec, 1.8 Pulmonic regurgitation, moderate or above,
• • 2. Patients who had undergone any operation on a cardiac valve (percutaneous balloon commissurotomy, valve repair, valve replacement, transcatheter aortic valve implantation),
• • 3. Diagnosis of endocarditis as assessed by Duke criteria.
• Exclusion Criteria:
• • 1. Patients cannot be followed up for any reasons.
• • 2. Patients in critical condition may be die in one year.
• • 3. Patients have been enrolled in this study.