MET: REevaluation for Perioperative cArdIac Risk (MET-REPAIR)
Launched by EUROPEAN SOCIETY OF ANAESTHESIOLOGY · Jan 9, 2017
Trial Information
Current as of June 13, 2025
Completed
Keywords
ClinConnect Summary
In spite of scarce and non-conclusive evidence on the prognostic value of self-reported functional capacity for perioperative cardiovascular events, the estimation of cardiovascular functional capacity in metabolic equivalents (METs) based on a questionnaire represent the core question in the preoperative cardiac risk assessment in patients undergoing elevated risk noncardiac surgery endorsed by ESA, the ESC, and the ACC/AHA. MET-REPAIR will examine the ability of MET estimated using a questionnaire to predict perioperative cardiovascular events correcting for preoperative risk factors, (e....
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Planned as Inpatients after surgery
- • 45 years of age or older AND undergoing elective elevated-risk noncardiac surgery as defined by either a Revised Cardiac Risk Index ≥ 2 \[9\] OR NSQIP MICA\>1% \[10\]
- • 65 years of age or older and undergoing intermediate or high-risk procedures \[3\]
- • Signed Written informed consent
- Exclusion Criteria:
- • Non-elective surgery, i.e. planned to occur ≤ 72 hours after diagnosis of the acute condition that makes the procedure necessary
- • Acute coronary syndrome or uncontrolled congestive heart failure within the last 30 days of planned day of surgery
- • Stroke within the last 7 days of planned day of surgery
- • Outpatients
- • Patients unable to perform ambulation due to congenital or longstanding illnesses/states (e.g. paraplegics, polio, etc; but explicitly not patients with fractures, needing hip replacement, etc.)
- • Unable to consent or unwilling to participate
- • Previous enrolment in MET REPAIR (in case of repeated surgery)
About European Society Of Anaesthesiology
The European Society of Anaesthesiology (ESA) is a leading professional organization dedicated to advancing the field of anaesthesiology through research, education, and collaborative practice. Committed to enhancing patient safety and outcomes, the ESA sponsors clinical trials that focus on innovative anaesthetic techniques, pain management, and perioperative care. By fostering a network of professionals and promoting evidence-based practices, the ESA plays a crucial role in shaping the future of anaesthesia and improving the quality of healthcare across Europe and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Düsseldorf, , Germany
Patients applied
Trial Officials
Giovanna Lurati Buse, PD Dr.
Study Chair
Heinrich-Heine University, Duesseldorf
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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