Natural History of Infants With Patent Processus Vaginalis

Launched by CHILDREN'S MERCY HOSPITAL KANSAS CITY · Feb 1, 2017

Keywords

ClinConnect Summary

This clinical trial is studying infants with a condition called Patent Processus Vaginalis (PPV), which can lead to inguinal hernias. Researchers want to understand how often and when these hernias occur in children who have undergone a specific type of surgery for another condition called pyloric stenosis. The study will follow participants from the time of their surgery until they are almost 18 years old, using annual phone calls or emails to check in on their health.

To be eligible for this trial, participants need to be infants under four months old who are having laparoscopic surgery for pyloric stenosis. However, those with certain conditions, like undescended testes or specific abdominal issues, cannot participate. If you choose to join, you will help contribute valuable information that could improve understanding and treatment of PPV and inguinal hernias in the future. The trial is currently recruiting participants and will continue until July 2025.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All patients having laparoscopic surgery for pyloric stenosis. Subjects are anticipated to be less than four months of age at the time of enrollment.
• • Enrollment inclusion dates: 08/2016 (upon IRB approval) to 7/31/2025
• Exclusion Criteria:
• • Patients who are anticipated to have a hostile abdomen for visualizing the inguinal rings (e.g. gastroschisis, necrotizing enterocolitis)
• • Patients who have unilateral or bilateral undescended testes
• • Patients undergoing open pyloromyotomy
• • Patients who have a known hernia