Hysterectomy and OPPortunistic SAlpingectomy

Launched by GÖTEBORG UNIVERSITY · Feb 4, 2017

Keywords

ClinConnect Summary

The HOPPSA trial is a research study looking at whether a procedure called opportunistic salpingectomy—removing the fallopian tubes during a hysterectomy for non-cancer reasons—can help reduce the risk of ovarian cancer without causing extra complications or affecting women's overall health. The study wants to see if this procedure can be safely performed on women under 55 years old who are already scheduled for a hysterectomy for benign (non-cancerous) reasons.

To be eligible for this trial, participants must be planning to have a hysterectomy for a benign issue and be willing to take part in the randomization process, which means they could either receive the surgery with or without the removal of the fallopian tubes. Women who have had previous surgeries to remove their ovaries or tubes, or have specific genetic risks for cancer, will not be included. If you join the study, your health will be monitored through national health records to help researchers gather important information about the long-term effects of this procedure.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Planned hysterectomy for a benign reason
• • Age \< 55 years at randomization
• • Willing to be randomized
• • Vaginal route may be included if the surgeon is confident with performing vaginal salpingectomy.
• Exclusion Criteria:
• • Previous bilateral oophorectomy and/or salpingectomy
• • Planned oophorectomy and/or salpingectomy (for reasons such as already diagnosed adnexal tumor, known carrier of the breast cancer susceptibility gene (BRCA) 1/2 mutation or Lynch syndrome (hereditary nonpolyposis colorectal cancer))
• • Non-understanding of the oral or written study information