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Search / Trial NCT03050671

Effects of External Leg Compression Devices on Healing and Blood Clotting

Launched by KAROLINSKA UNIVERSITY HOSPITAL · Feb 9, 2017

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

Aims:

1. To confirm that IPC (intermittent pneumatic compression) has a positive effect on systemic coagulation status, tissue metabolic activity, collagen formation and tissue microcirculation.
2. To compare the above effect of two different IPC devices: one rapid calf-IPC which expels blood from the veins sharp and rapidly and one slow calf-IPC, which pumps the blood in a more gentle and progressive way. This study could also make implications on how the blood flow parameters could be interpreted in the clinical setting, as previous haemodynamic studies have explained the superiority of ...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • Healthy individuals
  • Male gender
  • Age 18-60
  • Exclusion Criteria:
  • Smoking
  • Severe cardiovascular or renal disease causing pitting oedema
  • Previous operation in the lower limbs affecting the vascular or lymphatic system

About Karolinska University Hospital

Karolinska University Hospital is a leading academic medical center in Sweden, renowned for its commitment to advanced healthcare research and innovative clinical practices. As a key sponsor of clinical trials, the hospital leverages its extensive expertise in medical research and collaboration with Karolinska Institutet, one of the world's foremost medical universities. The institution is dedicated to enhancing patient care through rigorous scientific investigation, focusing on a wide range of therapeutic areas. With a multidisciplinary approach and a strong emphasis on translational medicine, Karolinska University Hospital aims to bridge the gap between laboratory findings and clinical application, ultimately striving to improve health outcomes and advance medical knowledge.

Locations

Stockholm, , Sweden

Patients applied

0 patients applied

Trial Officials

Paul Ackermann

Principal Investigator

Karolinska University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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