PERIODONTITIS AND VASCULAR DYSFUNCTION

Launched by UNIVERSITY COLLEGE, LONDON · Mar 1, 2017

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Participants must be ≥ 18 years-old.
• • 2. Participants must have moderate to severe periodontitis (at least 30 periodontal pockets \> 4mm with Bleeding on Probing) and radiographic signs of bone loss.
• • 3. Participants must have voluntarily signed the informed consent.
• Exclusion Criteria:
• • 1. Female participant is pregnant or lactating or of childbearing and not using acceptable methods of birth control.
• • 2. Participant is on chronic treatment (i.e., two weeks or more) with specific medications known to affect periodontal status (phenytoin or cyclosporine) within one month of baseline visit.
• • 3. Participant knowingly has HIV or Hepatitis.
• • 4. Participant has limited mental capacity or language skills such that simple instructions cannot be followed or information regarding adverse events cannot be provided.
• • 5. Participant on chronic antibiotic therapy or who require antibiotic coverage for periodontal procedures.
• • 6. Participant had a course of periodontal therapy in the preceding 6 month