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Search / Trial NCT03102554

Genetics of Differences of Sex Development and Hypospadias

Launched by BOSTON CHILDREN'S HOSPITAL · Mar 30, 2017

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Exome Sequencing

ClinConnect Summary

This clinical trial is focused on understanding the genetic reasons behind certain conditions that affect the development of genitals and reproductive organs, such as hypospadias (a condition where the opening of the urethra is not at the tip of the penis) and other genital or gonadal abnormalities. The researchers want to learn how these genetic findings impact families, particularly when they receive information about their child's condition.

To be eligible for this study, participants should have noticeable genital or gonadal abnormalities that haven't been explained by regular medical tests. This can include a range of conditions like hypospadias or ambiguous genitalia. The trial is currently active but not recruiting new participants. If involved, participants can expect to contribute to important research that may help future families facing similar challenges and gain insights into the genetic aspects of their conditions.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Genital or gonadal abnormalities as evidenced by physical examination or imaging (including but not limited to hypospadias, microphallus, clitoromegaly, ambiguous genitalia), with no cause identified by standard clinical evaluation
  • Exclusion Criteria:
  • Inability to provide informed consent

About Boston Children's Hospital

Boston Children's Hospital is a leading pediatric healthcare institution renowned for its commitment to advancing child health through innovative research and exceptional clinical care. As a prominent clinical trial sponsor, the hospital leverages its extensive expertise in pediatric medicine to conduct rigorous and ethically sound research studies aimed at improving treatment options and outcomes for children. With a collaborative approach that integrates cutting-edge technology and multidisciplinary teams, Boston Children's Hospital is dedicated to translating scientific discoveries into practical applications that enhance the well-being of young patients and their families.

Locations

Boston, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Yee-Ming Chan, MD, PhD

Principal Investigator

Boston Children's Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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