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Search / Trial NCT03103789

Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device

Launched by VANDERBILT UNIVERSITY MEDICAL CENTER · Mar 31, 2017

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

During routine esophagogastroduodenoscopy (EGD), consented study participants will have the original single channel MI catheter advanced through the working channel of the endoscope. Measurements will be taken at 3 locations for 5 seconds each. The catheter will then be removed and a custom-designed balloon assembly will be inserted through the working channel of the endoscope. The balloon assembly will expand to a maximum diameter of 2 cm spanning from the distal to mid esophagus and contain external metal contacts to form 40 impedance channels made up by 10 axial channels spanning a 10 cm...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients who are undergoing standard of care EGD with or without BRAVO pH capsule placement
  • Exclusion Criteria:
  • Age less than 18 years old
  • Patients unable to give informed consent
  • Use of acid suppressive therapy within last 10 days
  • Known history of Barrett's esophagus or gastric surgery, other than non-functioning (slipped) Nissen fundoplication

About Vanderbilt University Medical Center

Vanderbilt University Medical Center (VUMC) is a leading academic medical center located in Nashville, Tennessee, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, VUMC integrates cutting-edge scientific inquiry with patient-centered care, supporting a diverse array of studies aimed at enhancing medical knowledge and improving treatment outcomes. With a robust infrastructure and a multidisciplinary team of experts, VUMC fosters collaboration across various fields, ensuring the highest standards of safety and ethical considerations in its research endeavors. Through its dedication to medical discovery and education, VUMC plays a pivotal role in shaping the future of medicine.

Locations

Nashville, Tennessee, United States

Patients applied

0 patients applied

Trial Officials

Michael Vaezi, MD, PhD

Principal Investigator

Vanderbilt University Medical Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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