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A Randomized Trial of 4% Nebulized Lignocaine vs. 10% Lignocaine Spray in Patients Undergoing Flexible Bronchoscopy

Launched by POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH, CHANDIGARH · Apr 5, 2017

Trial Information

Current as of July 01, 2025

Completed

Keywords

ClinConnect Summary

Flexible bronchoscopy is common procedure used in the diagnosis and treatment of a variety of tracheobronchial diseases. The bronchoscope can be used to sample material not only from the visualized regions but also from the more distal pulmonary parenchyma. It is a safe outpatient exam that carries little risk. While performing the procedure most of the patients express some fear of pain, difficulty in breathing, nasopharyngeal irritation, and cough. During routine diagnostic flexible bronchoscopy, the most distressing symptom experienced by the patients is a cough, and control of a cough i...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age ≥18 years
  • Willing for flexible bronchoscopy procedure a
  • Exclusion Criteria:
  • Requirement of intravenous sedation to undergo any procedure including EBUS-TBNA, conventional TBNA, radial EBUS procedure and interventional pulmonary procedures
  • Sensitivity to lignocaine
  • Hemodynamically unstable patients (SBP \< 90 mm Hg)
  • Baseline hypoxemia (SpO2 \<92% on room air)
  • Pregnancy
  • Comorbid illness such as heart failure, CKD, chronic liver disease and others
  • Failure to provide informed consent

About Post Graduate Institute Of Medical Education And Research, Chandigarh

The Post Graduate Institute of Medical Education and Research (PGIMER) in Chandigarh is a premier institute dedicated to advancing medical education, research, and healthcare delivery in India. Renowned for its commitment to excellence, PGIMER plays a pivotal role in conducting cutting-edge clinical trials that contribute to the development of innovative therapies and improve patient outcomes. With a multidisciplinary approach and a team of highly qualified professionals, PGIMER fosters a collaborative environment for research, aiming to enhance medical knowledge and practice through rigorous scientific inquiry and evidence-based solutions.

Locations

Chandigarh, , India

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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