Patient Management During Major Abdominal Surgery: an Oxygen Consumption Protocol Compared to Standard Approach

Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Apr 12, 2017

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to manage patients during major abdominal surgeries, specifically focusing on how to ensure they receive the right amount of fluids and oxygen to support their bodies. The study compares the standard care method with a new approach called the NICE protocol, which aims to better match patients' needs. Participants will be divided into three groups: one receiving standard care, one following the NICE protocol, and another using a special method that measures how well the body uses oxygen. The goal is to improve patient outcomes by carefully managing fluid balance during surgery.

To be eligible for this trial, participants must be at least 18 years old and able to provide written consent. They should be scheduled for major abdominal surgeries lasting three hours or more. However, certain individuals will not be able to participate, including those with severe heart conditions, pregnant women, or those undergoing specific types of surgeries like liver or emergency procedures. If you join the study, you can expect to be monitored closely during your surgery and receive care tailored to your individual needs, which could help improve your recovery after the procedure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients aged \> 18 years
• • acquisition of written informed consent
• • Major abdominal surgery (major gastrointestinal surgery: DCP, gastrectomy, Miles, emicolectomy; gynecologic surgery: oncologic surgery) Surgery times ≥ 3 hours
• Exclusion Criteria:
• • Absolute contraindication to CVC placement
• • pregnant women
• • hepatic surgery
• • laparoscopic surgery
• • Major vascular surgery
• • Dialysis treatment and kidney transplant surgery
• • Severe heart failure (EF ≤ 35%)
• • Emergency surgery