A Randomized Trial to Assess the Role of Imaging During Follow Up After Radical Surgery of High Risk Melanoma

Launched by UPPSALA UNIVERSITY · Apr 11, 2017

Keywords

ClinConnect Summary

This clinical trial is studying whether regular imaging tests, like scans, during follow-up after surgery for high-risk melanoma can help improve patients' chances of survival. High-risk melanoma is a type of skin cancer that can be more aggressive and may come back after treatment. The researchers want to find out if these imaging tests are worth the effort and resources, especially since they can cause anxiety and expose patients to some radiation.

To participate in this study, you need to be at least 18 years old and have had surgery for a specific stage of melanoma. The trial is open to all genders and is currently looking for volunteers. If you join, you will receive either the standard follow-up care or more intense monitoring with additional imaging tests. This trial aims to provide valuable insights that could impact how doctors manage follow-up care for melanoma patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • At least 18 years of age.
• • Radical surgery for Cutaneous Malignant Melanoma (CMM) stage IIb-c and III.
• • Sufficient renal function for i.v. contrast scannings.
• Exclusion Criteria:
• • The patient is assessed as unfit to receive treatment in the case of recurrence.
• • Life-expectancy less than 2 years due to concurrent disease (e.g., cardiac disease, terminal multiple sclerosis, liver cirrhosis).
• • Inability to provide informed consent or refusal to do so.
• • Inability to comply with the control or intense follow-up program.
• • Participation in other clinical trials interfering with the control-program.
• • Existing or previous malignancies within the past 5 years (except for in situ breast and cervical cancer, melanoma in situ and non-melanoma skin cancer).
• • Pregnancy or currently planned pregnancy.