Outcome Analysis of POEM and Endoluminal Therapies

Launched by UNIVERSITY OF CALIFORNIA, DAVIS · Apr 17, 2017

Keywords

ClinConnect Summary

This trial is studying endoluminal (through-the-mouth) treatments for gastrointestinal conditions, with a focus on achalasia (trouble swallowing due to esophagus muscle problems) and problems that can occur after weight‑loss surgery, such as gastric/pouch fistulas. It looks at newer, less invasive endoscopic options like POEM and other endoluminal repair techniques to see how well they work compared with traditional surgery. The study is being conducted at the University of California, Davis, and is led by Dr. Mohamed R. Ali. No results are reported yet in the summary you provided.

Eligible participants are adults aged 18 through 80 who have gastrointestinal issues that may require surgery, including achalasia, GERD, Barrett’s esophagus, post-bariatric surgery problems, or related fistulas. If you’re considering this study, you would first learn about all treatment choices—surgery and endoscopic options—and decide whether to participate. If you enroll, you may receive an endoscopic treatment as part of the study, and researchers will follow your symptoms to see how they change. The main goal is to see if endoscopic therapies reduce reflux‑related distress within 3–6 months and whether achalasia symptoms improve about 30 days after treatment. The trial is ongoing and not randomized, with results not yet available here.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult male and female patients 18-80 years of age
• • Meet the criteria for surgery of benign and/or malignant gastrointestinal pathology(s)
• • Gastrointestinal Reflux Disease
• • Achalasia
• • Barrett's Esophagus
• • Post Bariatric Surgery conditions
• • Other gastrointestinal and postsurgical disorders.
• Exclusion Criteria:
• • Adults unable to consent
• • Individuals that do not meet inclusion criteria or qualify for endoluminal treatment paradigms and internees.