The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

Launched by SZEGED UNIVERSITY · Apr 28, 2017

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Eligibility criteria

• Inclusion Criteria:
• • 1. Adult (\>18 y)
• • 2. Critically ill anemic but hemodynamically stable patients treated on the ICU in whom transfusion is considered by the attending physician
• • 3. Routine ICU monitoring: invasive blood pressure, CVC, hourly urine output
• • 4. Anemia is defined as Hb\<100 g/L
• 5. Hemodynamic stability is defined as:
• • 1. heart rate (HR)\<100/min,
• • 2. mean arterial pressure (MAP)\>60 mmHg
• • 3. no or "minimal" requirement of noradrenaline (NA): compensation for sedation not exceeding 5 µg/min
• 4. stable homeostasis:
• • i. pH: 7.30-7.45 ii. HCO3 \> 20 mmol/L iii. lactate \< 2 mmol/L e. normal hourly urine output for the last 2 hours not facilitated by diuretics: \>0.5ml/kg/h
• • 6. Central venous catheter in situ (position in the v. cava superior confirmed by chest x-ray)
• Exclusion Criteria:
• • 1. Pregnancy
• • 2. Head injury requiring ICP monitoring guided control of ICP
• • 3. Shock of any origin
• • 4. Patients with heart failure
• • 5. Patients with renal failure