Biomechanical and Microstructural Properties of Ascending Aortic Aneurysms

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · May 2, 2017

Keywords

ClinConnect Summary

This clinical trial is focused on understanding the physical and structural characteristics of thoracic aortic aneurysms, which are bulges in the aorta caused by a weakening of the artery wall. The main goal is to create a better tool for diagnosing these aneurysms by studying their biomechanics and microstructure. This is important because current methods may not provide enough information to prevent serious complications, such as aortic rupture, which can be life-threatening.

If you or a loved one has a thoracic aortic aneurysm, whether you have symptoms or not, you might be eligible to participate in this study. The trial is open to all genders and is currently recruiting participants aged 65 to 74. Those who have experienced a ruptured aneurysm and are undergoing emergency surgery may also qualify. Participants will be asked to provide informed consent and may undergo tests to help researchers gather tissue samples for study. This research aims to improve how we diagnose and treat this serious condition, ultimately helping to save lives.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients suffering from thoracic aortic aneurysms (ATAA), asymptomatic or symptomatic.
• • Patients with ruptured ATAA undergoing an emergency surgery.
• • Signed informed consent.
• Exclusion Criteria:
• • Patients with ruptured ATAA due to trauma.
• • The presence of any aneurysm feature that will prevent the collection of tissue samples suitable for the biomechanical and microstructural studies.