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Search / Trial NCT03160066

The Effects of Lactobacillus Rhamnosus (JB-1) on Stress and Cognition

Launched by UNIVERSITY COLLEGE CORK · May 17, 2017

Trial Information

Current as of May 07, 2025

Completed

Keywords

Psychobiotic Brain Gut Axis Stress Cognition Eeg

ClinConnect Summary

30 healthy male volunteers will be recruited in a randomized single blind placebo controlled cross over trial. Study participation will involve a screening visit followed by a baseline cognitive test battery, EEG and stress visit (socially evaluated cold-pressor test). These measures will be repeated after 4 weeks of daily probiotic and placebo capsules.

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • able to give informed written consent
  • able to speak English
  • Exclusion Criteria:
  • having a significant acute or chronic illness
  • following a diet or taking a medication that would interfere with study objectives
  • pose a safety risk or confound the interpretation of the study results
  • evidence of immunodeficiency, bleeding disorder or coagulopathy
  • English not being participant's first language
  • colour blindness
  • dyslexia or dyscalculia
  • taking any probiotic products or antibiotics in the last 4 weeks
  • receiving any treatment involving experimental drugs

About University College Cork

University College Cork (UCC) is a leading research institution located in Ireland, renowned for its commitment to advancing healthcare through innovative clinical research. The university's clinical trial unit is dedicated to conducting high-quality, ethically sound studies that aim to improve patient outcomes and contribute to the scientific understanding of various medical conditions. UCC collaborates with a diverse network of healthcare professionals, researchers, and industry partners to facilitate pioneering trials across multiple therapeutic areas, ensuring adherence to the highest standards of regulatory compliance and patient safety. Through its initiatives, UCC strives to foster advancements in medicine and enhance the overall health of communities both locally and globally.

Locations

Cork, , Ireland

Patients applied

0 patients applied

Trial Officials

Ted Dinan, MD, PhD

Principal Investigator

University College Cork

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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