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Search / Trial NCT03163069

The Effect of Whitening Toothpaste on Tooth Color Associated With Bleaching Process

Launched by FUJIAN MEDICAL UNIVERSITY · May 19, 2017

Trial Information

Current as of November 01, 2025

Completed

Keywords

Tooth Bleaching Dentifrice

ClinConnect Summary

Sixty-three eligible participants (29 males and 34 females, mean age 26.1 years) with at least one maxillary tooth demonstrating shade A3 or darker will be recruited and randomly allocated into 3 groups (n = 21), according to the different dentifrices used in this clinical trial: Crest Total (regular dentifrice) for group C, Crest 3D Whitening (conventional whitening dentifrice) for group CW, and Close Up White Now (whitening dentifrice containing blue covarine) for group CU. All participants will receive in-office tooth bleaching with 40% hydrogen peroxide (Opalescence Boost PF 40%) for th...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • patients between 18 and 60 years of age, with fully erupted upper and lower incisors and canines without dental or periodontal disease or restorations, and with at least one maxillary tooth presenting color score A3 or darker, as measured with the Vita Classical guide (Vita Zahnfabrik, Bad Sa ̈ ckingen, Germany) ordered by brightness
  • Exclusion Criteria:
  • patients with systemic diseases or oral mucosal disorders, previous bleaching treatment, patients undergoing orthodontic treatment, pregnant women, people with known allergy to the product ingredients, smokers, and alcohol abusers.

About Fujian Medical University

Fujian Medical University is a prestigious academic institution located in Fujian Province, China, dedicated to advancing medical education, research, and clinical practice. With a strong emphasis on innovative healthcare solutions, the university actively engages in clinical trials to explore new therapeutic interventions and improve patient outcomes. Its comprehensive research programs are supported by a team of experienced professionals and state-of-the-art facilities, enabling the university to contribute significantly to the global medical community. Through its commitment to excellence and collaboration, Fujian Medical University aims to enhance the quality of healthcare delivery both locally and internationally.

Locations

Fuzhou, Fujian, China

Patients applied

0 patients applied

Trial Officials

Hao Yu

Principal Investigator

Fujian Medical University, China

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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