The Application of Impulse Oscillometry on the Diagnosis of ACOS,Asthma and COPD.
Launched by SHENGJING HOSPITAL · Jun 6, 2017
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new method called Impulse Oscillometry to help doctors better understand and diagnose conditions like Asthma-COPD Overlap Syndrome (ACOS), asthma, and chronic obstructive pulmonary disease (COPD) in patients over 40 years old. The goal is to see how well this method can tell the difference between these conditions, which can sometimes be confusing because they share similar symptoms, such as difficulty breathing.
To participate in this trial, individuals must be over 40 and meet specific criteria depending on their condition. For example, those with ACOS will need to show signs of both asthma and COPD, while asthma patients should have a history of symptoms that improve with treatment, and COPD patients should experience ongoing breathing problems. Participants can expect to undergo tests to measure their lung function, and all genders are welcome to join. This study is currently looking for volunteers, and it's an opportunity to contribute to research that could improve how these breathing conditions are diagnosed in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- - 1.1 ACOS:
- • 1. Patient is older than 40 years old.
- • 2. There are characteristics of bronchial asthma and COPD.
- • 3. There is a history of exposure to risk factors.
- • 4. Existence of persistent airflow limitation: After the application of bronchodilators, FEV1/FVC\<0.7, and lung function proved reversible exhalation.
- • 5. The existence of reversible airflow limitation: Bronchial Dilation Test positive.
- • 1.2Asthma: 1)Patient is older than 40 years old. 2)History of reversible respiratory symptoms. 3) non-smokers. 4)lung function:At least one time proved that the airflow limitation: Bronchial Dilation Test positive.
- 5)previously diagnosed asthma. 1.3COPD:
- • 1. Patient is older than 40 years old.
- • 2. Complaints about dyspnea, chronic cough or expectoration.
- • 3. There is a history of exposure to risk factors.
- • 4. Existence of persistent airflow limitation: After the application of bronchodilators, FEV1/FVC\<0.7.
- • 5. The existence of irreversible airflow limitation: Bronchial Dilation Test negative.
- Exclusion Criteria:
- • - 2.1 Combining other respiratory diseases that affect airflow,such as lung cancer, tuberculosis, pneumonia and bronchiectasis.
- • 2.2 At the time doing lung function test, the factors that affect the airflow limitation are not stopped or just stopped with the time interval not long enough to meet the test standard.
- • 2.3 Using special accompanying medication. For example, patients with drugs such as glucocorticoid.
About Shengjing Hospital
Shengjing Hospital, affiliated with the China Medical University, is a leading medical institution dedicated to advancing healthcare through innovative clinical research and trials. With a strong emphasis on multidisciplinary collaboration, the hospital leverages its state-of-the-art facilities and a team of experienced healthcare professionals to conduct comprehensive studies aimed at improving patient outcomes. Shengjing Hospital is committed to adhering to the highest ethical standards and regulatory guidelines, ensuring that all clinical trials are designed to enhance medical knowledge and provide safe, effective treatment options for diverse patient populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Shenyang, Liaoning, China
Patients applied
Trial Officials
LI ZHAO, Doctor
Study Director
SHENJING HOSPTIAL Affiliated to CHINA MEDICAL UNIVERSITY
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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