Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound

Launched by CARNEGIE MELLON UNIVERSITY · Jun 16, 2017

Keywords

ClinConnect Summary

This clinical trial is studying a new method called electrophysiological source imaging guided transcranial focused ultrasound (ESI-tFUS), which aims to improve how we understand and treat brain conditions. The goal is to see how this non-invasive technique can help manage brain activity in real-time. Researchers want to find out the best ways to use focused ultrasound to stimulate the brain while monitoring its effects, which could lead to better treatments for various brain-related issues in the future.

To participate in this study, you need to be a healthy adult aged 18 to 64 who can speak and understand English and is willing to give written consent. Unfortunately, if you have a serious medical condition, a history of seizures, or certain other neurological issues, you won't be eligible. Participants will undergo testing that involves the new ultrasound technique, and they will be closely monitored to assess how it affects brain activity. It's an exciting opportunity to contribute to research that could shape future brain therapies!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Apparently healthy volunteers.
• • Age 18-64.
• • Willing and able to provide written consent.
• • Able to communicate in the English language.
• Exclusion Criteria:
• Subjects having any of the following conditions will be excluded from this study:
• • Evidence of a current significant medical illness or psychiatric or central or peripheral neurologic disorder
• • History of loss of consciousness of more than ten minutes in the past year or loss of consciousness in a lifetime that required rehabilitation services
• • Personal or family history of seizure
• • Any history of stroke/transient ischemic attack (TIA)
• • Taking any medications that are known to decrease the threshold for seizure
• • Pregnancy
• • Affirmative answers to one or more questions of the provided attached safety questionnaires. These are not absolute contraindications to this study but the risk/benefit ratio will be carefully considered by the PI
• • Failure to follow laboratory or study procedures