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Search / Trial NCT03192501

iCAGES-guided Precision Therapy for Cancers in Contrast to Standard Care or IHC-guided Theray

Launched by SECOND AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIVERSITY · Jun 17, 2017

Trial Information

Current as of June 28, 2025

Recruiting

Keywords

Lung Cancer I Cages Gene Mutation Precision Medicine Advanced Cancers Ihc Targeted Therapy

ClinConnect Summary

This clinical trial is studying a new tool called iCAGES, which helps doctors tailor treatment for patients with advanced lung cancer and other serious cancers. The goal is to see if using this tool leads to better outcomes, such as longer time without disease progression and improved overall survival, compared to standard treatment methods or another approach based on immunohistochemistry (IHC). The trial is currently looking for participants and aims to understand if this precision therapy can enhance the quality of life for cancer patients.

To be eligible for the trial, participants must be between 18 and 70 years old, have a confirmed diagnosis of advanced or recurring lung cancer, and be willing to provide written consent. Unfortunately, individuals with a history of other cancers, those who are pregnant or breastfeeding, or those with certain serious health issues cannot take part. Participants can expect to receive personalized treatment based on the iCAGES tool, along with regular assessments to monitor their progress throughout the study. This trial is an opportunity to explore new, potentially more effective treatment options for advanced cancer.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Pathological and clinical diagnosis of recurrence / metastatic lung cancer or other advanced cancers.
  • There are PACS images available at the Second Affiliated Hospital of Guangzhou Medical University and the collaborated Hospitals.
  • The patient is informed consent and signed a written consent.
  • Exclusion Criteria:
  • Age \> 70 or \<18 years old.
  • Previous history of malignant tumors.
  • Pregnant or lactating female patients.
  • Any serious concomitant disease that is expected to have an adverse effect on prognosis, including the heart disease that treatment is required, unsatisfactory controlled diabetes and psychiatric disorders.

About Second Affiliated Hospital Of Guangzhou Medical University

The Second Affiliated Hospital of Guangzhou Medical University is a leading clinical research institution in Southern China, renowned for its commitment to advancing medical science through innovative research and high-quality patient care. As a prominent teaching hospital, it integrates clinical practice with research, fostering collaboration among healthcare professionals and academic experts. The hospital is dedicated to conducting rigorous clinical trials that adhere to ethical standards and regulatory requirements, aiming to enhance therapeutic options and improve patient outcomes across various medical disciplines. With state-of-the-art facilities and a multidisciplinary approach, the Second Affiliated Hospital is at the forefront of medical research and development.

Locations

Guangzhou, Guangdong, China

Patients applied

0 patients applied

Trial Officials

Zhenfeng Zhang, MD,PhD

Principal Investigator

Second Affiliated Hospital of Guangzhou Medical University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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