CAPA-VU Trial Catheter Ablation in Paroxymal Atrial Fibrillation Based on UNIVU

Launched by UNIVERSITÄTSKLINIKUM HAMBURG-EPPENDORF · Jun 22, 2017

Keywords

ClinConnect Summary

Catheter ablation (CA) has been established as a standard treatment especially in the setting of symptomatic paroxysmal atrial fibrillation (PAF) by means of pulmonary vein isolation (PVI) as recommended in the current guidelines. However, limitations regarding the success rate but also the x-ray burden with regard to patient and operator remain. One of the fundamental disadvantages of CA as it is routinely performed today, based on sequential application of radiofrequency current (RFC), is the need to verify the catheter position throughout the procedure by using fluoroscopy. Catheter guid...

Gender

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Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Written informed consent
• • Symptomatic Paroxysmal Atrial Fibrillation with indication for ablation
• Exclusion Criteria:
• • Age \< 18 years
• • Persistent or Permanent Atrial Fibrillation (failed Cardioversion or episode duration \> 12 months)
• • Previous surgical or interventional therapy of atrial fibrillation
• • BMI \> 30
• • Pregnant women or women of childbearing potential without a negative pregnancy test within 48 hours prior to treatment
• • History of hemorrhagic diathesis or other coagulopathies
• • Contraindications for oral anticoagulation
• • Hyper- or hypothyroidism
• • Has any condition that would make participation not be in the best interest of the subject