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Search / Trial NCT03202173

The Diagnosis of NPC Using the Probe-based Confocal Laser Endomicroscopy

Launched by EYE & ENT HOSPITAL OF FUDAN UNIVERSITY · Jun 27, 2017

Trial Information

Current as of August 02, 2025

Unknown status

Keywords

Probe Based Confocal Laser Endomicroscopy Optical Biopsy

ClinConnect Summary

The aim of this study was to depict the applicability of pCLE examinations for diagnosing NPC in comparison to the gold standard of histopathological examination, as well as developed an easy-to-use and straightforward scoring system for the identification of NPC on the basis of morphological and architectural criteria in order to enable a valid and reproducible CLE assessment even for non-experts in their daily clinical practice.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Male or female \> 18 years of age
  • 2. Indicated for nasal endoscope for indeterminate NPC
  • 3. Willing and able to comply with study procedures and provide written informed consent to participate in the study
  • Exclusion Criteria:
  • 1. Subjects for whom pCLE procedures are contraindicated
  • 2. Known allergy to fluorescein dye
  • 3. If female, pregnant based on a positive hCG serum or an in vitro diagnostic test result or breast-feeding

About Eye & Ent Hospital Of Fudan University

The Eye & ENT Hospital of Fudan University is a leading clinical research institution dedicated to advancing the fields of ophthalmology and otolaryngology. With a commitment to innovative medical practices and patient-centered care, the hospital integrates cutting-edge research with clinical expertise to conduct comprehensive clinical trials. Leveraging a multidisciplinary approach, the institution aims to enhance treatment modalities and improve patient outcomes through rigorous scientific investigation and collaboration with academic and industry partners. Its state-of-the-art facilities and experienced team of professionals position the Eye & ENT Hospital of Fudan University as a pivotal contributor to medical advancements in eye and ear, nose, and throat health.

Locations

Shanghai, Shanghai, China

Patients applied

0 patients applied

Trial Officials

Huawei Li, Phd &MD

Study Chair

Otorhinolaryngology Department of Affiliated Eye and ENT Hospital, Fudan University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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