Early Predictors of Necrotizing Enterocolitis in Neonates

Launched by NATIONWIDE CHILDREN'S HOSPITAL · Jul 5, 2017

Keywords

ClinConnect Summary

This clinical trial is focused on understanding how to identify early signs of a serious condition called Necrotizing Enterocolitis (NEC) in newborns. NEC is a disease that affects the intestines and can be life-threatening. The researchers aim to find out if certain non-invasive tests and specific biological markers can help spot infants who might be at risk of developing NEC before they show any symptoms. By identifying these infants early, the hope is to start treatments that could prevent the disease from getting worse.

To participate in this study, infants need to be born at 30 weeks or earlier or weigh less than 1500 grams at birth. Unfortunately, babies with certain conditions, like major heart problems or specific abdominal issues, won't be eligible for this trial. For families considering participation, the study is currently looking for volunteers, and it will provide information on what to expect during the process, ensuring that parents are well-informed and supported.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Infants born at ≤30 weeks gestational age and/or
• • Infants with a birth weight ≤1500 grams
• Exclusion Criteria:
• • gestational age at birth greater than 30 weeks
• • obvious dysmorphic syndromes
• • any abdominal wall defect including omphalocele or gastroschisis
• • any known intestinal atresia
• • complex cardiac abnormalities
• • any known lethal chromosomal abnormalities