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Search / Trial NCT03213756

Isometric Preoperative Exercise on Autologous Arteriovenous Fistulas. Randomized Clinical Trial

Launched by HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON · Jul 10, 2017

Trial Information

Current as of July 22, 2025

Completed

Keywords

Doppler Ultrasound Physical Exercise Arteriovenous Fistula Maturation

ClinConnect Summary

RECRUITING PERIOD: 20 months.

FOLLOW UP: From the first preoperative assessment visit for AVF up to 3 months after its creation.

METHODS:

After signing the informed consent, patients will be randomized through a centralized computer program to one of two groups of patients, PIE group versus control group.

In both groups of patients, a first physical examination of upper arm extremities and an initial doppler ultrasound will be performed, evaluating the anatomical and hemodynamic characteristics of the arteries and veins of both arms. At that time, a first surgical option of AVF will be ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Informed consent signature.
  • Age between 18 and 89 years.
  • Patients with advanced chronic kidney disease, stages IV-V, in pre-dialysis or prevalent HD patients, requiring new AVF.
  • Exclusion Criteria:
  • Absence of adequate arteries and veins to allow autologous AVF. (The minimum gauges that will be considered in order to perform an autologous AVF are: artery caliber equal or greater than 1.6 mm and vein caliber equal or greater than 1,8 mm with a compressor).
  • Diagnosis of coagulopathy or hemoglobinopathy of any cause.
  • Patients who urgently need an AVF without the possibility of being 8 weeks on the surgical waiting list.
  • Impossibility to perform the physical exercise protocol due to physical or mental disabilities or lack of social support.

About Hospital General Universitario Gregorio Marañon

The Hospital General Universitario Gregorio Marañón is a leading healthcare institution located in Madrid, Spain, renowned for its commitment to clinical excellence and innovative research. As a prominent clinical trial sponsor, the hospital combines advanced medical practices with cutting-edge research methodologies to facilitate the development of new therapies and improve patient outcomes. With a multidisciplinary team of experts and state-of-the-art facilities, the hospital actively engages in a wide range of clinical trials, contributing to the advancement of medical knowledge and the enhancement of healthcare delivery both locally and globally.

Locations

Madrid, , Spain

Patients applied

0 patients applied

Trial Officials

INES ARAGONCILLO, MD

Principal Investigator

GREGORIO MARAÑON HOSPITAL

ALMUDENA VEGA, MD PHD

Study Chair

GREGORIO MARAÑON HOSPITAL

SORAYA ABAD, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

NICOLAS MACIAS, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

JOSE MANUEL LIGERO, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

ROSARIO GARCIA PAJARES, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

ANGEL LUIS MORALES, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

TERESA CERVERA, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

JAVIER RIO, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

DIEGO RUIZ CHIRIBOGA, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

ELENA MENENDEZ, MD

Study Chair

GREGORIO MARAÑON HOSPITAL

MARTA ALBALATE, MD PHD

Study Chair

HOSPITAL INFANTA LEONOR

JARA AMPUERO, MD

Study Chair

HOSPITAL DEL SURESTE

COVADONGA HEVIA, MD

Study Chair

Hospital Infanta Sofia

SILVIA CALDES, MD

Study Chair

Hospital Infanta Sofia

YESIKA AMEZQUITA, MD

Study Chair

Hospital Infanta Sofia

YOLANDA HERNANDEZ, MD

Study Chair

Hospital Infanta Sofia

CRISTINA MORATILLA, MD PHD

Study Chair

CLINICA FUENSANTA

CARMEN CABRE, MD

Study Chair

CLINICA FUENSANTA

JOSE LUIS MARTIN CONTY

Study Chair

CASTILLA LA MANCHA UNIVERSITY

CRISTINA FERNANDEZ, MD PHD

Study Chair

Hospital Clinico de Madrid

ISRAEL LEBLIC, MD

Study Chair

Hospital Universitario La Paz

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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