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How do Super Lean Subjects Keep Resistant to Body Weight Gain?

Launched by CHINESE ACADEMY OF MEDICAL SCIENCES · Jul 13, 2017

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking into why some people remain very thin, or "super lean," even when obesity rates are rising in the general population. The researchers want to understand the lifestyles and genetic factors that allow these individuals to maintain a body mass index (BMI) below 18.5, which is considered very low. By studying both super lean individuals and those with a normal weight, they hope to find out what keeps some people resistant to weight gain.

To participate in this study, you need to be between 20 and 40 years old. If you have a BMI between 15 and 18 (for super lean participants) or between 20 and 25 (for control participants), and you are generally healthy without any eating disorders or diabetes, you may qualify. Women who are pregnant or breastfeeding cannot participate. If you join the study, you can expect to share information about your health and lifestyle, which will help researchers learn more about the reasons behind super lean body types. This research could provide important insights into obesity and health.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • control: BMI 20-25 kg/m2, healthy, age 20-40 years old superlean: BMI 15-18 kg/m2, healthy, with no eating disorders and diabetes, age 20-40 years old
  • Exclusion Criteria:
  • Pregnant women and women in lactation Subjects are suffering from eating disorders or diabetes.

About Chinese Academy Of Medical Sciences

The Chinese Academy of Medical Sciences (CAMS) is a premier national institution dedicated to advancing medical research and healthcare in China. As a leading sponsor of clinical trials, CAMS focuses on innovative therapies, disease prevention, and public health initiatives. With a robust infrastructure that encompasses research hospitals, laboratories, and collaboration with international partners, CAMS aims to enhance the translation of scientific discoveries into clinical practice. Their commitment to rigorous scientific standards and ethical conduct ensures the integrity and reliability of the trials they sponsor, ultimately contributing to improved health outcomes both domestically and globally.

Locations

Beijing, , China

Patients applied

0 patients applied

Trial Officials

John Speakman, PhD

Principal Investigator

Institute of Genetics and Developmental Biology

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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