Study for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Clinical Practice

Launched by NEUROLOGICAL ASSOCIATES OF WEST LOS ANGELES · Jul 26, 2017

Keywords

ClinConnect Summary

An MPRAGE is a high quality anatomical image of the brain. This is used as an anatomical overlay, so that all data collected from the advanced sequences below can be correlated with the correct brain areas in three dimensional space.

1. Resting BOLD - BOLD stands for blood oxygen level dependent. This functional sequence allows for the viewing of the thinking brain at rest, and looks at brain areas that are functionally working together at the same time. The brain is in one of its most active states when it is at rest, and literature has shown that a few neurological illnesses such as OCD,...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• In order for a subject to be considered for this study, the following criteria are required:
• • The subject is between the ages of 18-65 years old.
• • The subject clinically needs an advanced MRI
• • The subject has consented for his/her self.
• • The subject is fluent in the English language.
• • The subject is proficient in comprehending verbal and written English.
• Exclusion Criteria:
• • In order for a subject to be considered for this study, he/she may NOT have any of the following items which cannot be removed prior to the MRI exam. A subject who can remove any of the following prior to the MRI exam will still be considered for the study.
• • Aneurism clips
• • Cardiac pacemaker
• • Implanted cardioinverter defibrillator
• • Electronic implant or device
• • Magnetically activated implant or device
• • Neurostimulation system
• • Spinal cord stimulator
• • Internal electrodes or wires
• • Bone growth/bone fusion stimulator
• • Cochlear, otologic, or other ear implant
• • Insulin or other infusion pump
• • Implanted drug infusion device
• • Any type of prosthesis (eye, penile, etc.)
• • Heart valve prosthesis
• • Eyelid spring or wire
• • Artificial or prosthetic limb
• • No Metallic stent, filter, or coil
• • Shunt (spinal or intraventricular)
• • Vascular access port and/or catheter
• • Radiation seeds or implants
• • Swan-Ganz or thermodilution catheter
• • Medication patch (Nicotine, Nitroglycerine)
• • Any metallic fragment or foreign body
• • Wire mesh implant
• • Tissue expander (e.g., breast)
• • Surgical staples, clips, or metallic sutures
• • Joint replacement (hip, knee, etc.)
• • Bone/joint pin, screw, nail, wire, plate, etc.
• • IUD, diaphragm, or pessary
• • Dentures or partial plates
• • Tattoo or permanent makeup
• • Body piercing jewelry
• • Hearing aid
• As well as:
• • Breathing problem or motion disorder
• • Severe claustrophobia
• Any subjects from the following categories/groups will NOT be included in the study:
• • Prisoners
• • Minors
• • Poor/uninsured
• • Institutionalized
• • Limited or non-readers
• • Non-English speaking subjects
• • Wards of the state
• • Pregnant women
• • Nursing home residents recruited in the nursing home
• • Students of PI or study staff
• • Students recruited in the educational setting (school, class, etc)
• • Employees directly supervised by the PI or sub-investigator
• • Employees of research site or sponsor
• • Military personnel recruited by military personnel
• • Cognitively impaired
• • Adult subjects that cannot consent for themselves