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Search / Trial NCT03242980

Short Adherence Intervention for Viral Re-suppression

Launched by SWISS TROPICAL & PUBLIC HEALTH INSTITUTE · Aug 7, 2017

Trial Information

Current as of July 21, 2025

Completed

Keywords

Hiv Adherence Viral Re Suppression Step Wedgged Randomized Trial

ClinConnect Summary

Due to a lack of routine viral load (VL) monitoring in Lesotho until now, most health care workers in the districts lack the necessary information on how to manage patients with elevated viral loads. The CART-1 study found re-suppression rates of only 30% with only 70% returning for a second VL. From these estimates, it is clear that the current practice for managing these patients must be improved. A simple intervention has been designed that could be feasibly adapted at all health centres in Lesotho.

To ensure that the effect of this intervention is measured and to avoid a long delay in ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients receiving VL monitoring at one of the 2 hospitals and 10 health centres in Butha-Buthe district
  • Patients on first-line ART
  • Patients with a VL≥ 1000 copies/mL after a minimum of 6 months on first-line ART
  • Exclusion Criteria:
  • Patients receiving VL monitoring at a non-participating center in Butha-Buthe

About Swiss Tropical & Public Health Institute

The Swiss Tropical and Public Health Institute (Swiss TPH) is a leading research organization dedicated to enhancing global health through innovative scientific research, education, and capacity building. Based in Basel, Switzerland, Swiss TPH focuses on infectious diseases, global health systems, and public health interventions, aiming to translate scientific findings into practical solutions for communities in need. With a multidisciplinary team of experts, the institute collaborates with international partners to conduct clinical trials and implement evidence-based strategies that address pressing health challenges, particularly in low- and middle-income countries. Through its commitment to excellence and sustainability, Swiss TPH plays a pivotal role in advancing health equity and improving health outcomes worldwide.

Locations

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Butha Buthe, , Lesotho

Patients applied

0 patients applied

Trial Officials

Tracy R Glass, PhD

Principal Investigator

Swiss TPH

Niklaus Labhardt, MD

Study Chair

Swiss TPH

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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