Validation of the TOF Cuff Monitor® Which Measures Neuromuscular Block on the Upper Arm

Launched by CHRISTOPH CZARNETZKI · Aug 21, 2017

Keywords

ClinConnect Summary

Neuromuscular blocking agents (NMBAs) are frequently used in anesthesia for tracheal intubation, artificial ventilation, and continued muscle relaxation during surgical interventions. It is of particular importance to measure the neuromuscular block for several reasons:

1. To monitor the onset of neuromuscular block and to intubate when deep muscular relaxation is attained.
2. To choose the best antagonist and its dosage dependent of the degree of neuromuscular block (for instance sugammadex for deep neuromuscular block or neostigmine for superficial block).
3. To avoid antagonization of n...

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Eligibility criteria

• Inclusion Criteria:
• • Patients, age ≥18 to 65 years
• • Patient with American Society of Anesthesiology \[ASA\] status I or II
• • Patient able to read and understand the information sheet and to sign and date the consent form
• • Patient scheduled for elective surgery lasting at least 60 minutes
• Exclusion Criteria:
• • Patient with a history of allergy or hypersensitivity to rocuronium
• • Patient with pacemaker
• • Patients with neuromuscular disease
• • Patients with preoperative medications known to influence neuromuscular function (for instance aminoglycosides, phenytoin, lidocaine)
• • Patients with electrolyte abnormalities (for instance, hypermagnesemia)
• • Patients with a body mass index \<19 or \>30 kg m2
• • Patient having participated in any clinical trial within 30 days, inclusive, of signing the informed consent form of the current trial
• • Patients undergoing interventions that need a continuous deep NMB (for surgical reasons).