Effects of TENS and IES on the Autonomous Balance of Normotens Volunteers and Hypertensive Patients
Launched by UNIVERSIDADE FEDERAL DE SANTA MARIA · Aug 18, 2017
Trial Information
Current as of July 06, 2025
Completed
Keywords
ClinConnect Summary
Each volunteer will perform three assessments with a one-week interval. Each assessment will include assessment of autonomic balance, blood pressure, and blood collection (catecholamines). Interventions (placebo, low frequency TENS and IES) will be randomized. Volunteers will be accommodated in the supine position. With properly sanitized skin (70% alcohol) and self-adhesive electrodes (5x5 area) will be positioned in the cervical paravertebral region. All participants will be submitted to a placebo TENS session, a low frequency TENS session (TENS, 10 Hz/200μs) and an IES session (STEIN et ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Both sexes;
- • Normal blood pressure (PAS \<130 mmHg; PAD \<85 mmHg) or Previous Hypertension diagnosis, systolic blood pressure (SBP) \> 140 mm Hg and/or diastolic blood pressure (DBP) \>90 mm Hg and clinical stability with no change in medications for at least 2 months preceding the study;
- • The subjects that joined the study will be alphabetized volunteers;
- • Age between 20 and 65 years old;
- • With no symptoms of skeletal muscle disorders;
- • No previous performing cardiovascular surgery;
- • No previous diagnose of rheumatic, neurological, oncological, immune or hematologic diseases;
- • Without evidence of psychiatric diseases and/or cognitive déficit;
- • Non-Smoker;
- • Volunteers with a body mass index (BMI: kg/m2) greater than 35 will not be included in the study
- Exclusion Criteria:
- • On the day of the assessments who have consumed of the alcoholic drink, caffeine and citrus juice and who have performed intense physical activities 48 before the examination
About Universidade Federal De Santa Maria
The Universidade Federal de Santa Maria (UFSM) is a prominent Brazilian academic institution known for its commitment to advancing research and education in the health sciences. As a clinical trial sponsor, UFSM leverages its extensive resources and expertise to conduct innovative studies aimed at improving patient outcomes and contributing to the scientific community. The university fosters a collaborative environment, engaging multidisciplinary teams of researchers, healthcare professionals, and students to ensure rigorous methodology and adherence to ethical standards in clinical research. Through its focus on cutting-edge medical research, UFSM plays a vital role in addressing health challenges and enhancing the quality of care in Brazil and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Santa Maria, Rio Grande Do Sul, Brazil
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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