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Search / Trial NCT03264261

Constraint Induced Movement Therapy for Walking in Individuals Post Stroke

Launched by SHIRLEY RYAN ABILITYLAB · Aug 24, 2017

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Stroke, Locomotion

ClinConnect Summary

This clinical trial is studying two different types of therapy to see which one helps people who have had a stroke improve their walking ability. The researchers want to compare Constraint Induced Movement Therapy (CIMT), which focuses on using the affected side of the body, to treadmill training alone. Participants will be randomly assigned to one of these two groups and will take part in training sessions three times a week for six weeks. Each session will last about 45 minutes, and their walking ability will be assessed at the beginning, middle, and end of the study.

To be eligible for this trial, participants need to be between the ages of 21 and 75 and have experienced a stroke that affects one side of their body. They should also have difficulty walking (meaning they walk slower than 0.80 meters per second) but can stand and walk at least 10 meters without help. Participants with serious heart or respiratory issues, other injuries affecting their ability to walk, or certain other health conditions will not be able to join. This study is currently looking for volunteers, and it aims to include 36 participants. If you or someone you know fits the criteria and is interested in improving walking after a stroke, this could be a great opportunity.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. age between 21 and 75 years;
  • 2. history of unilateral, supratentorial, ischemic or hemorrhagic stroke;
  • 3. no prior stroke;
  • 4. demonstration of impaired walking function (self-selected walking speed ≤ 0.80 m/s);
  • 5. able to stand and walk (\>10 meters) without physical assistance.
  • Exclusion Criteria:
  • 1. significant cardiorespiratory/metabolic disease;
  • 2. other neurological or orthopedic injury that impairs locomotion;
  • 3. scores on the Mini Mental Status examination \< 24;
  • 4. stroke of the brainstem or cerebellar lesions;
  • 5. uncontrolled hypertension (systolic \> 200 mm Hg, diastolic \> 110 mm Hg);
  • 6. botox injection within 6 months of starting the study.

About Shirley Ryan Abilitylab

Shirley Ryan AbilityLab is a leading research and rehabilitation institute dedicated to advancing the science of physical medicine and rehabilitation. Based in Chicago, Illinois, the organization integrates clinical care, research, and education to enhance the quality of life for individuals with disabilities and chronic conditions. Known for its innovative approach, Shirley Ryan AbilityLab conducts clinical trials that aim to develop and evaluate cutting-edge therapies and technologies, fostering a collaborative environment that bridges the gap between laboratory research and patient care. Through its commitment to excellence, the institute strives to empower patients and improve outcomes in rehabilitation medicine.

Locations

Chicago, Illinois, United States

Patients applied

0 patients applied

Trial Officials

Ming Wu, PhD

Principal Investigator

Abilitylab

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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