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Search / Trial NCT03304665

Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies

Launched by NATIONAL INSTITUTE OF MENTAL HEALTH (NIMH) · Oct 6, 2017

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

Healthy Volunteer Mental Health Common Data Elements

ClinConnect Summary

This clinical trial is looking for healthy adult volunteers to help with research studies at the National Institutes of Health (NIH) in Bethesda, Maryland. The goal is to gather information about the brain and how it functions in people who are in good health. By participating, volunteers will help create a set of brain scan images that researchers can use to better understand what is considered "normal" brain activity. This information will be shared with other scientists to advance research in mental health.

To be eligible, you must be between 18 and 70 years old and in good health, meaning you don’t have serious medical or mental health issues that need treatment. If you're interested, you'll start by filling out an online questionnaire about your health and background. If everything looks good, you'll come in for an in-person assessment where you’ll have a physical exam and some tests, including a possible brain scan if you choose to do so. Your data will be kept private and used to support future research. This is a great opportunity to contribute to important health studies while learning more about your own health.

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • 18 - 70 years of age.
  • Able to read, speak, and understand English.
  • Able to provide informed consent.
  • In current good general health.
  • EXCLUSION CRITERIA:
  • Have a history of significant or unstable medical or mental health condition requiring treatment, such as heart or lung disease, depression or psychosis.
  • Endorse current self-injury, suicidal thoughts or behavior.
  • Have current illicit drug use by history or urine drug screen.
  • Are found to have an abnormal physical exam or laboratory result that may require treatment or further evaluation.
  • Less than an 8th grade education.
  • Pregnancy.
  • Positive HIV test as HIV positivity has been associated with neurological changes.
  • Optional Brain MRI scan exclusion criteria:
  • Metal in body which would make having an MRI scan unsafe.
  • Being uncomfortable in small, closed spaces such as the MRI machine.
  • Inability to lie comfortably on back for at least 45 minutes.
  • Pregnancy.
  • Optional MEG recording exclusion criteria:
  • -Metal in body which would cause artifacts on MEG recordings.

About National Institute Of Mental Health (Nimh)

The National Institute of Mental Health (NIMH) is a leading federal agency dedicated to advancing the understanding and treatment of mental health disorders through innovative research and clinical trials. As part of the National Institutes of Health (NIH), NIMH focuses on a broad spectrum of mental health issues, including mood disorders, anxiety disorders, schizophrenia, and developmental disorders. By fostering collaboration among researchers, clinicians, and the community, NIMH aims to translate scientific discoveries into effective interventions and improve mental health outcomes for individuals across the lifespan. Through its commitment to rigorous research methodologies and ethical standards, NIMH plays a pivotal role in shaping the future of mental health care and policy.

Locations

Bethesda, Maryland, United States

Patients applied

SD

CO

2 patients applied

Trial Officials

Carlos A Zarate, M.D.

Principal Investigator

National Institute of Mental Health (NIMH)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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