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Search / Trial NCT03322917

Ocular Surface Syndrome Post-lasik, Outcomes of Treatment With Platelet Rich Plasma

Launched by VISSUM, INSTITUTO OFTALMOLÓGICO DE ALICANTE · Oct 23, 2017

Trial Information

Current as of June 20, 2025

Completed

Keywords

Dry Eye Prp Autologous After Lasik Ocular Surface

ClinConnect Summary

Prospective interventional consecutive case series including 156 eyes of 80 patients affected by chronic post-LASIK OSS who were treated with autologous E-PRP 6 times a day as monotherapy for 6 weeks. Assessment after treatment with E-PRP included: dry eye symptoms, change in corrected distance visual acuity (CDVA), corneal fluorescein staining (CFS) and conjunctival hyperemia.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult patients suffering from moderate to severe dry eye syndrome for 6 months or more after conventional treatments with artificial tears following LASIK.
  • Tear break-up time (TBUT) between 4 and 9 seconds.
  • Exclusion Criteria:
  • Ocular pathology needing topical treatments different than dry eye syndrome
  • Trombocitopeny, associated pathologies to coagulation factors or any state of plaquets antiagregation (AAS and other AINES).
  • Ocular tumours, corneal distrophies, history of ocular herpes.
  • Pregnant or nursering women.

About Vissum, Instituto Oftalmológico De Alicante

Vissum, Instituto Oftalmológico de Alicante, is a leading clinical research organization specializing in ophthalmology. With a commitment to advancing eye care through innovative research, Vissum conducts rigorous clinical trials aimed at evaluating cutting-edge treatments and technologies for a range of ocular conditions. The institute is equipped with state-of-the-art facilities and a team of experienced professionals dedicated to improving patient outcomes and contributing to the scientific community's understanding of vision-related health. Through collaboration with global partners, Vissum plays a pivotal role in shaping the future of ophthalmic therapies.

Locations

Patients applied

0 patients applied

Trial Officials

JORGE L ALIO, DR.

Principal Investigator

Vissum, Instituto Oftalmológico de Alicante

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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