Comparing Proposed Algorithm and Current Practice in the Evaluation of Suspected Appendicitis
Launched by SINGAPORE GENERAL HOSPITAL · Oct 24, 2017
Trial Information
Current as of June 25, 2025
Unknown status
Keywords
ClinConnect Summary
Acute appendicitis is one of the most common causes of acute abdominal pain requiring surgical intervention, with a lifetime risk of 8.6% for males and 6.7% for females. Historically, negative appendectomy rates of more than 20% were considered the norm. This is no longer acceptable in the current era, as despite low complication rates in the setting of negative appendectomy, conditions such as incisional hernias, intestinal obstruction secondary to adhesions and stump leakages can still result in significant morbidity.
Computed Tomography (CT) scan has emerged as the dominant imaging moda...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients between the ages of 21 to 80 who are admitted to Singapore General Hospital and Sengkang Health for suspected appendicitis based on admission diagnosis from the Emergency Department
- Exclusion Criteria:
- • Patients who are pregnant
- • Patients below 21 or above 80 years of age
- • Patients with generalized peritonitis on presentation
- • Patients with palpable right iliac fossa mass on presentation
- • Patients with evidence of acute confusional state/dementia
- • Patients at high risk of surgery (ASA\>4) from the study
- • Patients who are immunocompromised (on chemotherapy, steroids etc.)
About Singapore General Hospital
Singapore General Hospital (SGH) is a leading academic medical center in Singapore, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent clinical trial sponsor, SGH plays a pivotal role in conducting cutting-edge studies that aim to improve patient outcomes and enhance medical knowledge across various specialties. With a strong focus on collaboration and multidisciplinary approaches, SGH leverages its extensive resources and expertise to facilitate rigorous clinical trials, ensuring the highest standards of safety and efficacy in the development of new treatments and therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Singapore, , Singapore
Singapore, , Singapore
Patients applied
Trial Officials
Tan Jianhong Winson, MBBS
Principal Investigator
Singapore General Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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