Autonomic Modulation in Takotsubo Syndrome

Launched by NYU LANGONE HEALTH · Oct 25, 2017

Keywords

ClinConnect Summary

This clinical trial is investigating how a special breathing program might help people with Takotsubo Syndrome, a condition that can cause temporary heart problems often triggered by stress. The study will involve 20 participants: 10 individuals who have a history of Takotsubo Syndrome and 10 healthy people of the same age and sex for comparison. Participants will have their heart and nerve function tested in a lab and then will follow a 15-week program where they practice device-guided breathing at home. The researchers want to see if these home measurements are reliable and if this breathing technique improves heart function and overall quality of life for those with Takotsubo.

To be eligible for this trial, participants must have a confirmed history of Takotsubo Syndrome. Healthy individuals can also join, but they shouldn't have significant heart or brain conditions. Those with implanted devices like pacemakers, certain nerve diseases, diabetes, or a history of substance abuse won't be able to participate. If you join, you'll be actively involved in a study that aims to contribute important information about managing Takotsubo Syndrome and potentially improving the lives of those affected by it.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Confirmed history of takotsubo syndrome
• • Healthy person with no significant past history of cardiovascular or neurological disease such as heart failure or heart attack; people with cardiovascular risk factors such as hypertension will be permitted to participate
• Exclusion Criteria:
• • Pacemaker or defibrillator implanted
• • Evidence of autonomic neuropathy, alcohol or drug abuse or exposure to neurotoxins (chemotherapy).
• • Diabetes