Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women

Launched by INNOVACION Y DESARROLLO DE ESTRATEGIAS EN SALUD · Dec 4, 2017

Keywords

ClinConnect Summary

Randomized controlled trial, aimed to evaluate the efficacy of Lactobacillus reuteri DSM 16666/ATCC 55845 \& Lactobacillus reuteri DSM 17938 for the treatment of pregnant women with asymptomatic bacteriuria or uncomplicated acute cystitis. As primary outcome we will evaluate the number of cases with clinical (symptoms severity) or bacteriological cure in pregnant women with uncomplicated cystitis or asymptomatic bacteriuria after 7 days treatment with probiotics vs. placebo. As secondary outcome we will evaluate a) rate of recurrence cases in each group; b) time to relapse; c) frequency of ...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Healthy women on the second or third trimester of pregnancy with positive urine culture according to the operational definition with or without symptoms
• • Age 18 to 40 years
• • Verbal and Written Informed Consent for participation in the study
• Exclusion Criteria:
• • Pathologic pregnancy (different for UTI)
• • No supplementation of probiotics 2 weeks before study start or during the study period.
• • Antibiotic therapy within last 2 weeks before randomization
• • Known allergies towards the ingredients of the experimental product
• • Inability to comprehend the study protocol
• • Systemic diseases
• • Multiple pregnancy