Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment

Launched by KYOWA HAKKO BIO CO., LTD. · Dec 7, 2017

Keywords

ClinConnect Summary

This study is a 12-week, randomized, double-blind, placebo-controlled trial of citicoline in healthy men and women with Age-Associated Memory Impairment. Cognitive assessments will be performed to determine whether citicoline administration with supportive memory, compared to placebo administration.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • male or female, 50-85 years of age
• • at least a high school diploma or the equivalent
• • self-reported memory loss
• • scores ≥24 on the Mini-Mental State Examination, ≥85 on the Kaufman Brief Intelligence Test, Second Edition, ≤5 on the Geriatric Depression Scale, and 4, 3, or 2 on the Spatial Span Test
• • no health conditions that would prevent him or her from fulfilling the study requirements on the basis of medical history and routine laboratory test results
• Exclusion Criteria:
• • color blind
• • abnormal laboratory test results
• • major medical or neurological illness
• • female who is pregnant, planning to be pregnant during the study period
• • requiring treatment with a drug which might obscure the action of the study treatment