In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells

Launched by MAYO CLINIC · Dec 22, 2017

Keywords

ClinConnect Summary

This clinical trial is looking at how healthy bone marrow plasma cells use a substance called glutamine, which is important for energy production in our bodies. Researchers want to see if they can measure this process effectively in living people (in vivo) compared to measuring it in samples taken from the body (ex vivo). This study is still in the early stages and is currently recruiting participants.

To be eligible for this trial, you must be between 18 and 60 years old and able to give your written consent to participate. Some people may not qualify if they have certain health conditions, like kidney failure, active liver disease, or anemia, among others. If you decide to take part, you can expect to undergo some tests that will help researchers understand how your body uses glutamine. This study is important because it may help improve our understanding of how healthy cells function, which could have implications for various health conditions in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Ages 18-60
• • Able to provide written consent
• Exclusion Criteria:
• • Renal Failure
• • Pregnancy
• • Active steroid use
• • Active liver Disease
• • Anemia (Hemoglobin \< 12.5 g/dL in men and \< 11.5 g/dL in women)
• • H/O alcohol use (average \> 2 drinks per day)
• • BMI \> 30