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Search / Trial NCT03394833

Hemodynamic Stability During Induction of Anaesthesia

Launched by UMEÅ UNIVERSITY · Jan 8, 2018

Trial Information

Current as of July 08, 2025

Completed

Keywords

Preoperative Fluid Therapy Hemodynamics Anesthesia Induction Rapid Sequence Induction Tci

ClinConnect Summary

40 individuals are enrolled to TCI and RSI groups respectively. The randomization process for preoperative fluid bolus prior to induction of anaesthesia is conducted in respective group at the day of surgery. Preoperative colloid fluid therapy (6 ml/kg LBW, Gelofusine™, Fresenius Kabi Ab, Sweden) is infused rapidly before non-invasive baseline blood pressure (NIBP) measurements in twenty individuals in each group. No other intravenous fluids before induction of anaesthesia.

NIBPs, pulse frequency, peripheral saturation (SpO2) are registered and collected 20 minutes post induction.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 80 individuals over 18 years, body mass index ≤ 35 kg/m2, electively scheduled for breast cancer surgery, endocrinologic surgery (thyroid, parathyroid) and general abdominal surgery.
  • Exclusion Criteria:
  • instable angina pectoris at the day of surgery, severe bronchial asthma or COPD.

About Umeå University

Umeå University, a leading research institution in Sweden, is dedicated to advancing healthcare through innovative clinical trials and translational research. With a strong emphasis on interdisciplinary collaboration, the university harnesses cutting-edge technology and expert knowledge across various fields to address critical health challenges. Its commitment to ethical standards and patient safety ensures that all clinical trials conducted under its auspices are designed to generate robust scientific evidence, ultimately contributing to improved health outcomes and informed medical practices. Umeå University strives to foster a dynamic research environment that supports the development of new therapies and enhances the understanding of complex health issues.

Locations

Luleå, , Sweden

Patients applied

0 patients applied

Trial Officials

Tomi P Myrberg, MD PhD

Principal Investigator

Umeå University, Norrbotten county concil

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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