Pre- and Apnoeic Oxygenation for RSI in ED

Launched by NATIONAL UNIVERSITY HOSPITAL, SINGAPORE · Jan 4, 2018

Keywords

ClinConnect Summary

Maintaining adequate oxygenation during rapid sequence intubation (RSI) is imperative to prevent peri-intubation adverse events that can lead to increased duration of hospital and intensive care unit stay, or prolonged vegetative state requiring long-term institutionalisation.

Preliminary data from our emergency department (ED) airway registry revealed that 15% of patients experienced desaturation during intubation despite employing current best practices during RSI. In this multicentre randomised controlled trial in the ED, we aim to test the hypothesis that use of humidified high flow ox...

Gender

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Eligibility criteria

• Inclusion Criteria:
• • Adult patients aged 21 years and above, who require RSI due to medical, surgical and traumatic conditions, in the Emergency Departments of NUH and Ng Teng Fong General Hospital (NTFGH)
• Exclusion Criteria:
• • Patients with "do-not-resuscitate" orders
• • Crash, awake or delayed sequence intubations
• • Patients requiring non-invasive positive pressure ventilation
• • Cardiac arrest
• • Clinical suspicion or confirmed diagnosis of base of skull fractures or severe facial trauma that precludes nasal cannula placement
• • Vulnerable patient populations (e.g. pregnant women, prisoners)