FreeDom: Innovative Strategy for the Management of COPD Exacerbations

Launched by LAVAL UNIVERSITY · Jan 9, 2018

Keywords

ClinConnect Summary

The FreeDom clinical trial is exploring a new approach to help patients with Chronic Obstructive Pulmonary Disease (COPD) who are experiencing worsening symptoms, known as exacerbations. The main goal of the trial is to see if this innovative strategy, which includes early discharge from the hospital, a special oxygen delivery system, and support through telemedicine and rehabilitation, can help reduce the number of days patients need to stay in the hospital by 50% within 30 days.

To participate in this study, candidates must be at least 40 years old, have recently been hospitalized for a COPD exacerbation (within the last 48 hours), and require moderate oxygen therapy. However, some individuals may not be eligible, such as those needing immediate mechanical breathing assistance or those who live alone and are not able to care for themselves at home. Participants can expect to receive personalized support and monitoring through the new system, which aims to improve their recovery and reduce hospital stays.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All patients hospitalized for COPD exacerbation for less than 48 hours will be considered.
• • known or suspected COPD to entry
• • Age \> or = 40 years
• • Ex-smoker history (10 pack / year or more)
• • Acute Exacerbation: dyspnea of recent onset (less than 15 days)
• • The need for oxygen therapy with a moderate rate: \<6L / min to maintain SpO2 \> 90% (for oxygen dependent patient, the oxygen flow must be higher than flow at home)
• Exclusion Criteria:
• • Refusal to consent to participate in the study,
• • Indication for an imminent intubation according to the pulmonologist,
• • Sleep Apnea
• • NIV used at home
• • Lack of FreeO2 system available at the time of randomization
• • Non-autonomous and alone at home
• • Patient alone at home
• • Patients who live more than 50 km from the hospital
• • Patient already included in the study within 3 months