Peripheral Nerve Blocks for Above-the-knee Amputations

Launched by UNIVERSITY OF FLORIDA · Jan 11, 2018

Keywords

ClinConnect Summary

This clinical trial is studying the use of nerve blocks and sedation during above-the-knee amputations to see if they can provide safer and more effective pain relief compared to traditional general anesthesia and opioid medications. This is particularly important for patients who are at higher risk due to conditions like diabetes, heart disease, or lung problems. The goal is to improve the overall experience and safety for these patients during surgery.

To participate in the trial, patients should be between the ages of 65 and 74 and scheduled for an above-the-knee amputation or knee disarticulation. They must also be able to understand and give consent for the procedure. However, individuals who have certain allergies, severe liver issues, or those who are pregnant cannot participate. If you or someone you know is eligible, they can expect to receive either nerve block anesthesia or general anesthesia during surgery, and the team will monitor their comfort and safety closely throughout the process.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing above-the-knee amputation or knee disarticulation
• • Ability to understand and provide informed consent
• Exclusion Criteria:
• • Patient refusal or inability to provide informed consent
• * True allergy, not sensitivity, to any of the following substances:
• • - Local anesthetics
• • - Propofol or other sedative agents
• • - General anesthetic agents
• • Pregnancy
• • Severe hepatic impairment
• • Evidence of infection at or near the proposed needle insertion site
• • Any sensorimotor deficit, whether acute or chronic, as determined by the PI
• • Chronic use of opioid medication
• • BMI ≥ 35