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Search / Trial NCT03419260

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Launched by CHILDREN'S HOSPITAL OF PHILADELPHIA · Jan 31, 2018

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Seizures Status Epilepticus Eeg Monitoring

ClinConnect Summary

This clinical trial is studying how to better manage electrographic seizures in critically ill children. Electrographic seizures are a type of seizure that can be detected using a special test called EEG (electroencephalogram). These seizures are common in patients in the Pediatric Intensive Care Unit (PICU), and the study aims to understand which children are most at risk for having them. Researchers will track these patients to identify risk factors and develop models that help healthcare providers monitor those at the highest risk effectively. Additionally, the trial will evaluate the safety of the current treatments used for managing these seizures.

To be eligible for this study, participants must be between 1 month and 18 years old and receiving care in the Children's Hospital of Philadelphia's Pediatric ICU with a need for continuous EEG monitoring. However, children who are expected to stop receiving life support in the next two days or are admitted for special EEG monitoring will not be included. Families participating in the trial can expect to provide information about their child's condition while researchers observe how well the current seizure management strategies work for their child. This research is important for improving care and outcomes for children with seizures in critical situations.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Care in the Children's Hospital of Philadelphia Pediatric ICU.
  • 2. Clinically indicated continuous EEG monitoring.
  • 3. Age \> 1 month to 18 years.
  • Exclusion Criteria:
  • 1. Admitted for Phase 2 (intracranial) EEG monitoring.
  • 2. Intensivist expects to discontinue technological support in the next two days given underlying medical or neurological problems.

About Children's Hospital Of Philadelphia

The Children's Hospital of Philadelphia (CHOP) is a leading pediatric healthcare institution renowned for its commitment to advancing child health through innovative research and clinical care. As a prominent clinical trial sponsor, CHOP emphasizes a multidisciplinary approach to pediatric research, fostering collaborations across various specialties to develop and evaluate groundbreaking therapies and interventions. With a focus on improving patient outcomes and enhancing the quality of life for children, CHOP is dedicated to conducting rigorous clinical trials that adhere to the highest ethical standards and scientific integrity, ultimately contributing to the global knowledge base in pediatric medicine.

Locations

Philadelphia, Pennsylvania, United States

Patients applied

0 patients applied

Trial Officials

Nicholas S Abend, MD

Principal Investigator

Children's Hospital of Philadelphia

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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