Comparison of the Effects of Lower Limb Immobilisation With Cast and Orthosis
Launched by KAROLINSKA UNIVERSITY HOSPITAL · Feb 1, 2018
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how different types of leg immobilization—using a cast versus a special supportive device called an orthosis—affect blood flow in the legs. The researchers want to understand how these two methods influence blood circulation, especially for people with conditions like venous stasis and deep venous thrombosis. The trial is currently looking for healthy participants aged between 65 and 74 years.
To be eligible for this study, you should be in good health and not have any serious heart or kidney problems, previous surgeries on your legs that could affect blood flow, or be pregnant. If you join the trial, you will be assessed for your blood flow while wearing either a cast or an orthosis, helping researchers learn more about the best ways to manage blood circulation in the legs. Your participation could contribute valuable information to medical science!
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Healthy individuals
- Exclusion Criteria:
- • Severe cardiovascular or renal disease causing pitting oedema
- • Previous operation in the lower limbs affecting the vascular or lymphatic system
- • Pregnancy
About Karolinska University Hospital
Karolinska University Hospital is a leading academic medical center in Sweden, renowned for its commitment to advanced healthcare research and innovative clinical practices. As a key sponsor of clinical trials, the hospital leverages its extensive expertise in medical research and collaboration with Karolinska Institutet, one of the world's foremost medical universities. The institution is dedicated to enhancing patient care through rigorous scientific investigation, focusing on a wide range of therapeutic areas. With a multidisciplinary approach and a strong emphasis on translational medicine, Karolinska University Hospital aims to bridge the gap between laboratory findings and clinical application, ultimately striving to improve health outcomes and advance medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Stockholm, , Sweden
Stockholm, , Sweden
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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