Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients With Cocaine Addiction

Launched by SALVATORE CAMPANELLA · Feb 5, 2018

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called N-acetylcysteine (NAC) on patients recovering from cocaine addiction. Cocaine addiction can lead to a strong urge to use the drug again, known as craving, even after stopping for a while. The researchers want to see if NAC can help reduce these cravings and prevent patients from relapsing back into drug use. Participants in this study will be patients who have recently completed a detox program and are abstinent from cocaine. They will be French-speaking individuals, aged between 18 and 65, who have been admitted to the hospital for a three-week stay.

If you or someone you know is interested in participating, it's important to note that certain conditions may exclude someone from joining. For instance, if a person is taking medications to reduce cravings or has a history of other significant medical conditions, they may not qualify. Throughout the study, participants can expect to receive NAC treatment over a period of about three to four weeks, and researchers will monitor how effective the medication is in helping manage their cravings. This trial could be an important step in finding new ways to support people recovering from cocaine addiction.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients addicted to cocaine (according to the DSM V classification)
• • Patients admitted for three weeks in the unit 73 of the CHU Brugmann Hospital
• • French speaking
• Exclusion Criteria:
• • Anti-craving or anti-psychotic medication
• • Addiction to other drugs (except nicotine or cannabis)
• • Neurological medical history
• • Psychiatric medical history
• • Heavy medical history
• • Asthma
• • Pregnancy
• • Lactose intolerance